30 is very playable. You want to shoot for something over 60. Once you get higher than that, you really can't tell the difference because your eyes have a refresh rate of their own
Even you clean up your computer, you're not going to have much of a difference in framerate. Freeing up disk space is not going to lighten the load the game puts on your CPU by much. Nonetheless, it's still something I recommend doing on a regular basis. Use CCleaner to get rid of temporary files and such. You can let it keep your cookies and whatever so not all of your browsing data is lost.